Joe Lonsdale: American Optimist

Joe Lonsdale: American Optimist โดย Joe Lonsdale

Joe Lonsdale

Welcome to American Optimist hosted by Joe Lonsdale, entrepreneur, investor, and founder of four multi-billion dollar companies and other mission-driven organizations. American Optimist is an alternative to the fear, cynicism, and zero-sum thinking in mainstream media. Learn from the innovators and leaders who are solving our nation’s most pressing challenges -- and doing it in a way that will lift everyone up. Hope should dominate our discourse, and American Optimist will show you why.

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Sebastian Caliri is Partner at 8VC with a focus on healthcare investing. Previously, Sebastian spent four years at Palantir where he was responsible for growing its commercial healthcare business. In this episode, Sebastian diagnoses the core problems in U.S. healthcare and explains why traditional fee-for-service care misaligns incentives, resulting in rising costs and inferior health outcomes. He makes the case for new models like value-based care and also highlights the potential of psychedelic medicine and other exciting innovation. Sebastian holds a BS and MS in Molecular Biophysics & Biochemistry from Yale University and spent a year in Stanford's MD program before pursuing a career in tech and investing. He argues that the conventional path in medicine is broken and often produces a risk-averse, complacent culture; he challenges the next generation of doctors and health care professionals to think boldly and take on the status quo.


  • 39 - Psychedelic Medicine, Value-Based Care & Why Medical School Is Broken with Sebastian Caliri 
    Tue, 09 Aug 2022 - 0h
  • 38 - Tony Fadell on Creating the iPod, iPhone, & Nest Thermostat 
    Fri, 20 May 2022 - 0h
  • 37 - Zach Latta: Building Hack Club & Inspiring the Next Generation of Coders 
    Wed, 27 Apr 2022 - 0h
  • 36 - Gene Berdichevsky and Sila’s Game-Changing Battery Technology 
    Thu, 21 Apr 2022 - 0h
  • 35 - Reprogramming Cells, Decentralizing Pharma, and Understanding the Biotech Revolution. 
    Mon, 18 Apr 2022 - 0h

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